Document Detail

Spinal extradural schwannoma.
MedLine Citation:
PMID:  15871485     Owner:  NLM     Status:  MEDLINE    
OBJECT: The authors endeavor to define the clinical and surgery-related profile of spinal nerve sheath tumors located in the extradural space outside both the dural sac and, apparently, the nerve roots' sleeve. METHODS: A series of 24 extradural schwannomas was retrospectively selected after reviewing the notes of spinal nerve sheath tumors surgically treated at La Sapienza University of Rome. Clinical data, tumor-related characteristics, and outcome were analyzed. Women predominantly harbored these tumors. On admission sensory nerve root dysfunction was infrequently reported, whereas pyramidal tract deficits were often present. The tumor, generally large, was most frequently located in the intermediate thoracic segments and high cervical region; only one was reported in the lumbosacral region. Considerable erosion of vertebral bodies was reported in almost one third of the cases. In four patients eloquent nerve roots, that of C-5 in three and that of S-1 in one, were involved with the tumor. Radical tumor resection, with preservation of the nerve roots, was possible in several cases, whereas in two patients manipulation and resection of the C-5 root produced transient and permanent, respectively, root palsy. At follow-up examination patients for whom walking was impossible before surgery were now able to walk. CONCLUSIONS: Extradural schwannomas can be distinguished from other nerve sheath tumors growing inside the spinal canal by their clinicoradiological features and unlikely nerve root origin. After surgery, recovery from pyramidal tract deficits, even severe, is noteworthy; in the authors' experience, however, resection of an involved appendicular root is more likely to result in a permanent and significant radicular deficit.
Paolo Celli; Giuseppe Trillò; Luigi Ferrante
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery. Spine     Volume:  2     ISSN:  1547-5654     ISO Abbreviation:  -     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-05-05     Completed Date:  2005-05-31     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  101223545     Medline TA:  J Neurosurg Spine     Country:  United States    
Other Details:
Languages:  eng     Pagination:  447-56     Citation Subset:  IM    
St Andrea Hospital, Department of Neurological Sciences, Rome, Italy.
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MeSH Terms
Cervical Vertebrae / pathology
Follow-Up Studies
Lumbar Vertebrae / pathology
Magnetic Resonance Imaging
Middle Aged
Movement Disorders / etiology
Nerve Sheath Neoplasms / complications,  pathology,  surgery*
Neurilemmoma / pathology,  surgery*
Postoperative Period
Pyramidal Tracts / physiopathology
Recovery of Function
Retrospective Studies
Sacrum / pathology
Spinal Nerve Roots / pathology,  surgery*
Thoracic Vertebrae / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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