Document Detail

Spinal epidural lipomatosis: case reports, literature review and meta-analysis.
MedLine Citation:
PMID:  15795966     Owner:  NLM     Status:  MEDLINE    
BACKGROUND CONTEXT: Symptomatic spinal epidural lipomatosis (SEL), a rare cause of spinal cord compression, has most often been associated with exogenous steroid use. PURPOSE: Identify four associations with SEL, correlate the associated groups with level of disease and compare treatment with outcome data in these groups. STUDY DESIGN/SETTING: Case reports of three patients and analysis of 104 cases from the literature. PATIENT SAMPLE: Three patients from the senior author's practice. OUTCOME MEASURES: Not applicable. METHODS: The authors report three new cases of SEL not associated with steroid use. They review all available English literature and present a table of all 104 reported cases. RESULTS: The clinical course of three new patients is reported. CONCLUSIONS: Associated conditions are exogenous steroid use, obesity, endogenous steroid excess, and some remain idiopathic. Although SEL is a rare condition, our review of the literature reveals many more reported cases than previously thought. With increased awareness of this condition and improved imaging techniques, further studies of this disease should be undertaken.
Guy R Fogel; Paul Y Cunningham; Stephen I Esses
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Publication Detail:
Type:  Case Reports; Journal Article; Meta-Analysis    
Journal Detail:
Title:  The spine journal : official journal of the North American Spine Society     Volume:  5     ISSN:  1529-9430     ISO Abbreviation:  Spine J     Publication Date:    2005 Mar-Apr
Date Detail:
Created Date:  2005-03-29     Completed Date:  2005-06-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101130732     Medline TA:  Spine J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  202-11     Citation Subset:  IM    
Houston Spine Surgery, TX 77007, USA.
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MeSH Terms
Epidural Space / pathology
Glucocorticoids / adverse effects
Lipomatosis / chemically induced,  pathology*,  surgery
Middle Aged
Spinal Cord Compression / chemically induced,  pathology*,  surgery
Treatment Outcome
Reg. No./Substance:

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