Document Detail

Spinal cryptococcoma in an immunocompetent cat.
MedLine Citation:
PMID:  18783789     Owner:  NLM     Status:  MEDLINE    
This report describes an unusual case of primary cryptococcoma in the proximal thoracic spinal cord of an 11-year-old immunocompetent cat from a farm on which there were large numbers of pigeons. This animal was referred for examination with progressive paralysis and shown to be free from feline immunodeficiency virus, feline leukaemia virus, feline coronavirus and Toxoplasma gondii. It died 2 months later. At necropsy, the only lesion detected was a malacic area, 4cm in length, in the spinal cord. Histopathological examination of the spinal cord revealed severe granulomatous inflammation associated with large numbers of encapsulated yeast cells. In addition to the granulomatous host response, necrosis, digestion chambers, Gitter cells, spheroids and lymphocytic perivascular cuffs were features of the malacic areas. Immunohistochemistry confirmed the presence of Cryptococcus neoformans var. grubii yeast cells.
S Belluco; J L Thibaud; J Guillot; M B Krockenberger; M Wyers; S Blot; M A Colle
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-09-09
Journal Detail:
Title:  Journal of comparative pathology     Volume:  139     ISSN:  0021-9975     ISO Abbreviation:  J. Comp. Pathol.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-12-10     Completed Date:  2009-02-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0102444     Medline TA:  J Comp Pathol     Country:  England    
Other Details:
Languages:  eng     Pagination:  246-51     Citation Subset:  IM    
Unité d'Anatomie-Pathologique, UMR 703 INRA/ENVN, Ecole Nationale Vétérinaire de Nantes, France.
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MeSH Terms
Cat Diseases / microbiology*,  pathology*,  physiopathology
Cryptococcosis / pathology*,  physiopathology,  veterinary*
Cryptococcus neoformans
Spinal Cord Diseases / microbiology*,  pathology,  veterinary*
Thoracic Vertebrae

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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