Document Detail


Spinal cord stimulation for the treatment of vascular pathology.
MedLine Citation:
PMID:  24262897     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Multiple studies have shown proved efficacy of spinal cord stimulation (SCS) in peripheral vascular disease (PVD). The exact mechanism by which SCS acts in the treatment of PVD is not completely understood, and may include stimulating the release of nitric oxide, modulation of the sympathetic nervous system, or modulation of prostaglandin production. Patient selection criteria have been well defined and SCS should be reserved for patients with end-stage lower limb PVD unresponsive to medical therapy and not amenable to surgical reconstruction but in whom disease has not caused inevitable limb loss. This article reviews the outcomes, techniques, patient selection criteria, and putative mechanisms of SCS for PVD.
Authors:
Milind Deogaonkar; Zion Zibly; Konstantin V Slavin
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Publication Detail:
Type:  Journal Article     Date:  2013-10-05
Journal Detail:
Title:  Neurosurgery clinics of North America     Volume:  25     ISSN:  1558-1349     ISO Abbreviation:  Neurosurg. Clin. N. Am.     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2013-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9008004     Medline TA:  Neurosurg Clin N Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  25-31     Citation Subset:  IM    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
Affiliation:
Department of Neurosurgery, Ohio State University, 480 Medical Center Drive, Columbus, OH 43210, USA.
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