Document Detail

Spinal cord infarction associated with primary antiphospholipid syndrome in a young child. Case report.
MedLine Citation:
PMID:  8360745     Owner:  NLM     Status:  MEDLINE    
Antiphospholipid antibodies have been reported to occur in ischemic stroke patients, but there have been no previous reports linking these antibodies to spinal cord infarction. A case of spinal cord infarction associated with primary antiphospholipid syndrome in a 6-year-old boy is reported. Magnetic resonance imaging clearly demonstrated marked swelling of the thoracolumbar spinal cord with gadolinium-diethylenetriamine pentaacetic acid enhancement at an acute stage, followed later by cord atrophy. Serological study disclosed positive lupus anticoagulant and immunoglobulin G anticardiolipin antibody. It is suggested that the role of antiphospholipid antibodies as an etiological factor for spinal cord ischemia should be recognized among causes that might have been categorized as either spontaneous spinal cord infarction or myelitis.
M Hasegawa; J Yamashita; T Yamashima; K Ikeda; Y Fujishima; M Yamazaki
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurosurgery     Volume:  79     ISSN:  0022-3085     ISO Abbreviation:  J. Neurosurg.     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-09-28     Completed Date:  1993-09-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0253357     Medline TA:  J Neurosurg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  446-50     Citation Subset:  AIM; IM    
Department of Neurosurgery, Kanazawa University School of Medicine, Japan.
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MeSH Terms
Antibodies, Anticardiolipin / analysis
Antiphospholipid Syndrome / complications*,  immunology
Contrast Media
Gadolinium DTPA
Infarction / complications*,  diagnosis
Lupus Coagulation Inhibitor / analysis
Magnetic Resonance Imaging
Organometallic Compounds / diagnostic use
Pentetic Acid / diagnostic use
Spinal Cord / blood supply*,  pathology
Reg. No./Substance:
0/Antibodies, Anticardiolipin; 0/Contrast Media; 0/Lupus Coagulation Inhibitor; 0/Organometallic Compounds; 67-43-6/Pentetic Acid; 80529-93-7/Gadolinium DTPA

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