Document Detail

Spinal anaesthesia with 0.5% hyperbaric bupivacaine in elderly patients: effect of site of injection on spread of analgesia.
MedLine Citation:
PMID:  8949807     Owner:  NLM     Status:  MEDLINE    
In this randomized, observer-blind study, we have examined, in elderly patients, the effect of site of injection on analgesia levels after spinal injection of 0.5% hyperbaric bupivacaine solution. Thirty male patients, aged 68-87 yr, undergoing minor urological surgery during spinal anaesthesia received 3 ml of a 0.5% hyperbaric bupivacaine solution at either the L3-4 (n = 15) or L4-5 (n = 15) interspace. The solution was injected with the patient in the sitting position. The patient remained sitting for 2 min and was then placed in the supine horizontal position. Analgesia levels were assessed bilaterally using pin-prick. The highest analgesia levels did not differ between groups (medians were approximately T7). There were no significant differences in the time to maximum cephalad spread of analgesia, maximum degree of motor block or haemodynamic changes. We conclude that injection at the L4-5 interspace has no advantage compared with injection at the L3-4 interspace.
B T Veering; P M Ter Riet; A G Burm; R Stienstra; J W Van Kleef
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  77     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-01-07     Completed Date:  1997-01-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  343-6     Citation Subset:  IM    
Department of Anaesthesiology, University Hospital Leiden, Netherlands.
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MeSH Terms
Aged, 80 and over
Anesthesia, Spinal / methods*
Anesthetics, Local / administration & dosage*,  pharmacokinetics,  pharmacology
Bupivacaine / administration & dosage*,  pharmacokinetics,  pharmacology
Hemodynamics / drug effects
Single-Blind Method
Urinary Tract / surgery
Reg. No./Substance:
0/Anesthetics, Local; 2180-92-9/Bupivacaine
Comment In:
Br J Anaesth. 1997 Jul;79(1):144-5   [PMID:  9301405 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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