Document Detail

Spinal Cord Stimulation for Electrical Storm Refractory to Conventional Medical Treatment: An Emerging Indication?
MedLine Citation:
PMID:  24917386     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To observe the effect of thoracic spinal cord stimulation with dual octipolar epidural electrodes on episodes of ventricular tachycardia and ventricular fibrillation in a patient with nonischemic familial cardiomyopathy and severe electrical storm refractory to conventional medical treatment.
RESULTS: Following implantation of temporary bilateral octipolar thoracic epidural electrodes and constant low-grade stimulation, episodes of ventricular tachycardia and ventricular fibrillation were eradicated, and a permanent system was surgically implanted uneventfully. Electrical storm ceased thereafter, though ventricular function from progressive cardiomyopathy worsened, requiring heart transplantation several months later.
CONCLUSIONS: Spinal cord stimulation may play an important therapeutic role in the treatment of refractory electrical storm when conventional medical treatments have failed. The mechanism by which stimulation of the spinal cord confers a therapeutic effect is not completely understood, although direct modulation of sympathetic and parasympathetic tone in the cardiac conduction system is most likely, based on animal models of ischemia-induced ventricular tachycardia.
David Walega; Joshua M Rosenow
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-10
Journal Detail:
Title:  Neuromodulation : journal of the International Neuromodulation Society     Volume:  -     ISSN:  1525-1403     ISO Abbreviation:  Neuromodulation     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9804159     Medline TA:  Neuromodulation     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2014 International Neuromodulation Society.
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