Document Detail

Spina bifida occulta and monozygotic twins.
MedLine Citation:
PMID:  18831659     Owner:  NLM     Status:  MEDLINE    
Central nervous system maldevelopment can have different presentations in twins. We report on a case of different presentations of spina bifida occulta in monozygotic twins. The first twin presented at birth with a lipomyelomeningocele; a tethered cord was diagnosed in the second twin at 2 years of age. Neural tube defects (NTDs) are a group of common congenital malformations of the brain and spine generated during neurulation. The genetic basis of this process is still not well known. Whenever an NTD is diagnosed in one of a pair of twins, the other twin should also be evaluated for NTDs.
Barbara Spacca; Neil Buxton
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Publication Detail:
Type:  Journal Article; Twin Study    
Journal Detail:
Title:  Journal of neurosurgery. Pediatrics     Volume:  2     ISSN:  1933-0707     ISO Abbreviation:  -     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-03     Completed Date:  2008-10-23     Revised Date:  2009-02-19    
Medline Journal Info:
Nlm Unique ID:  101463759     Medline TA:  J Neurosurg Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  258-60     Citation Subset:  IM    
Department of Neurosurgery-Littlewoods Neuroscience Unit, Royal Liverpool Children's Hospital NHS Trust, Liverpool, United Kingdom.
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MeSH Terms
Child, Preschool
Diseases in Twins*
Infant, Newborn
Spina Bifida Occulta*
Twins, Monozygotic

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