Document Detail


Spin lock and magnetization transfer MR imaging of local liver lesions.
MedLine Citation:
PMID:  9665546     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present study was designed to evaluate tissue contrast characteristics obtained with the spin-lock (SL) technique by comparing the results with those generated with a magnetization transfer(MT)-weighted gradient echo [GRE, echo-time (TE)=40 ms] sequence. Twenty-eight patients with hepatic hemangiomas (n=14), or metastatic liver lesions (n=14) were imaged at 0.1 T by using identical imaging parameters. Gradient echo, single-slice off-resonance MT, and multiple-slice SL sequences were obtained. SL and MT-effects were measured from the focal liver lesions and from normal liver parenchyma. In addition, tissue contrast values for the liver lesions were determined. Statistically significant difference between the SL-effects of the hemangiomas and metastases, and also between the MT-effects of the lesions was observed (p < 0.02). Tissue contrast values for the lesions proved to be quite similar between the SL and MT techniques. Our results indicate that at 0.1 T multiple-slice SL imaging provides MT based tissue contrast characteristics in tissues rich in protein with good imaging efficiency and wide anatomical coverage, and with reduced motion and susceptibility artifacts.
Authors:
J T Halavaara; R E Sepponen; A E Lamminen; T Vehmas; S Bondestam
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Magnetic resonance imaging     Volume:  16     ISSN:  0730-725X     ISO Abbreviation:  Magn Reson Imaging     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-09-15     Completed Date:  1998-09-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8214883     Medline TA:  Magn Reson Imaging     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  359-64     Citation Subset:  IM    
Affiliation:
Department of Radiology, Helsinki University Central Hospital, Finland. jhalavaa@helsinki.fi
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Artifacts
Biopsy, Needle
Breast Neoplasms / pathology
Colonic Neoplasms / pathology
Diagnosis, Differential
Female
Follow-Up Studies
Hemangioma / pathology*
Humans
Liver Neoplasms / pathology*,  secondary
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Prospective Studies
Reproducibility of Results
Comments/Corrections
Erratum In:
Magn Reson Imaging 1998 Nov;16(9):1146

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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