| Sphincter of Oddi: Function, dysfunction, and its management. | |
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MedLine Citation:
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PMID: 19799700 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The most common functional disorder of the biliary tract and pancreas relates to the activity of the Sphincter of Oddi. The Sphincter of Oddi is a small smooth muscle sphincter strategically placed at the junction of the bile duct, pancreatic duct, and duodenum. The sphincter controls flow of bile and pancreatic juices into the duodenum and prevents reflux of duodenal content into the ducts. Disorder in its motility is called Sphincter of Oddi dysfunction. Clinically this presents either with recurrent abdominal biliary type pain or episodes of recurrent pancreatitis. Manometry may identify the motility abnormalities, the most clinically significant being an abnormally elevated basal pressure. The most effective treatment once an abnormal basal pressure is identified is division of the sphincter. This is associated with good long-term results. |
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Authors:
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James Toouli |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of gastroenterology and hepatology Volume: 24 Suppl 3 ISSN: 1440-1746 ISO Abbreviation: J. Gastroenterol. Hepatol. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-05 Completed Date: 2009-12-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607909 Medline TA: J Gastroenterol Hepatol Country: Australia |
Other Details:
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Languages: eng Pagination: S57-62 Citation Subset: IM |
Affiliation:
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Flinders University of South Australia, Adelaide, Bedford Park SA 5042, Australia. jim.toouli@flinders.edu.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Pain
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etiology,
physiopathology Analgesics, Opioid / therapeutic use Animals Biliary Tract Surgical Procedures / instrumentation Endoscopy Humans Manometry Pancreatitis / etiology, physiopathology Predictive Value of Tests Pressure Recurrence Sphincter of Oddi / physiopathology* Sphincter of Oddi Dysfunction / complications, diagnosis, physiopathology*, therapy Stents Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Opioid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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