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Spermatogenesis in cryptorchidism.
MedLine Citation:
PMID:  22144242     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Cryptorchidism or undescended testis is the most frequent congenital abnormality in newborn boys. The process of testicular descent to the scrotum is controlled by hormones produced in Leydig cells, insulin-like3, and androgens. Variation in genetic and environmental factors might affect testicular descent. A failure of spermatogenesis and germ cell apoptosis resulting in infertility as well as an increased risk of neoplastic transformation of germ cell are the direct consequences of cryptorchidism in adulthood.
Authors:
Alexander I Agoulnik; Zaohua Huang; Lydia Ferguson
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  825     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2012  
Date Detail:
Created Date:  2011-12-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  127-47     Citation Subset:  IM    
Affiliation:
Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA, Alexander.Agoulnik@fiu.edu.
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