| Spermatogenesis in cryptorchidism. | |
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MedLine Citation:
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PMID: 22144242 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cryptorchidism or undescended testis is the most frequent congenital abnormality in newborn boys. The process of testicular descent to the scrotum is controlled by hormones produced in Leydig cells, insulin-like3, and androgens. Variation in genetic and environmental factors might affect testicular descent. A failure of spermatogenesis and germ cell apoptosis resulting in infertility as well as an increased risk of neoplastic transformation of germ cell are the direct consequences of cryptorchidism in adulthood. |
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Authors:
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Alexander I Agoulnik; Zaohua Huang; Lydia Ferguson |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Methods in molecular biology (Clifton, N.J.) Volume: 825 ISSN: 1940-6029 ISO Abbreviation: Methods Mol. Biol. Publication Date: 2012 |
Date Detail:
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Created Date: 2011-12-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9214969 Medline TA: Methods Mol Biol Country: United States |
Other Details:
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Languages: eng Pagination: 127-47 Citation Subset: IM |
Affiliation:
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Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA, Alexander.Agoulnik@fiu.edu. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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