Document Detail

Review article: spermatocytic seminoma: review of the literature and description of a new case of the anaplastic variant.
MedLine Citation:
PMID:  21087978     Owner:  NLM     Status:  In-Data-Review    
The aims of this paper were to review the literature of Spermatocytic Seminoma (SS) updating its clinico-pathological features and to present a new case of the exceptionally rare variant of this tumor known as anaplastic which only five cases have been reported. Many studies have confirmed that SS is a distinct neoplasm both clinically and pathologically from classical Seminoma and it differs from the latter especially in regard to behavior, characterized by an almost complete inability to metastasize with only very few convincing examples described with metastatic behavior. There is general agreement that orchidectomy is sufficient therapy for SS and that surveillance following surgery is the preferred management option. Surprisingly, the presence of an anaplastic component does not seem to impact on this excellent prognosis. Very different is the case of sarcomatous transformation, for which further therapy after orchiectomy is advisable.
Mariano Lombardi; Mirca Valli; Massimo Brisigotti; Juan Rosai
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Publication Detail:
Type:  Journal Article     Date:  2010-11-17
Journal Detail:
Title:  International journal of surgical pathology     Volume:  19     ISSN:  1940-2465     ISO Abbreviation:  Int. J. Surg. Pathol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314927     Medline TA:  Int J Surg Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5-10     Citation Subset:  IM    
Dipartimento di Patologia e Medicina di Laboratorio U.O. di Anatomia Patologica- Azienda Ospedaliero-Universitaria-Parma,
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