Document Detail

Sperm tail agenesis in a case of consanguinity.
MedLine Citation:
PMID:  15193497     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To report a case of 100% teratozoospermia in a patient whose family history presented a high degree of consanguinity. DESIGN: Case report. SETTING: University-based andrology clinic. PATIENT(S): A 27-year-old man undergoing infertility evaluation. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Serum hormone analysis, standard (World Health Organization) semen quality evaluation, sperm ultrastructure, lymphocytic karyotype, and polymerase chain reaction screening for Y chromosome microdeletions in peripheral blood. RESULT(S): One hundred percent teratozoospermia characterized by shape alterations of the heads and tail agenesis on standard morphology evaluation, which was confirmed using electron microscopy. CONCLUSION(S): A case of familial infertility in a consanguineous patient characterized by morphological abnormalities of spermatozoa such as tail agenesis, chromatin subcondensation, and residual cytoplasmic droplets.
Maurizio Latini; Loredana Gandini; Andrea Lenzi; Francesco Romanelli
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  81     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2004 Jun 
Date Detail:
Created Date:  2004-06-14     Completed Date:  2004-07-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1688-91     Citation Subset:  IM    
Department of Medical Pysiopathology, University of Rome "La Sapienza.",Rome, Italy.
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MeSH Terms
Infertility, Male / etiology*,  pathology,  physiopathology
Microscopy, Electron
Sperm Count
Sperm Motility
Sperm Tail / ultrastructure*
Spermatozoa / abnormalities*

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