Document Detail

Specular microscopy of corneal endothelial cells in rabbits.
MedLine Citation:
PMID:  7492645     Owner:  NLM     Status:  MEDLINE    
The corneal endothelia of 19 male and 19 female Japanese White rabbits (age: 6 to 15 months) were examined with a contact-type specular microscope under general anesthesia. The specular microscopy showed uniform-sized, pentagonal or hexagonal endothelia arranged regularly on the innermost layer of the cornea. In addition, large endothelial cells were sporadically observed in some rabbits. These large cells had smooth contour, and were 3 to 15 times as large as the cells of standard size. The large cells were isolated from each other and randomly located in one or both eyes of both sexes in all age groups examined. The presence of large endothelial cells was not related with the wounds on the corneal surface or the inflammation in the anterior chamber. Concerning the cell density (cells/mm2) and the incidence of the large cell, no statistically significant difference was observed between the left and right eyes or between sexes. However, the cell density decreased in rabbits over 12 months old.
H Morita
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of veterinary medical science / the Japanese Society of Veterinary Science     Volume:  57     ISSN:  0916-7250     ISO Abbreviation:  J. Vet. Med. Sci.     Publication Date:  1995 Apr 
Date Detail:
Created Date:  1996-01-11     Completed Date:  1996-01-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9105360     Medline TA:  J Vet Med Sci     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  273-7     Citation Subset:  IM    
Preclinical Research Division, Central Institute for Experimental Animals, Kawasaki, Japan.
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MeSH Terms
Aging / physiology
Endothelium, Corneal / cytology*,  growth & development
Microscopy / methods
Rabbits / growth & development*
Sex Characteristics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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