| Spectrum of single photon emission computed tomography/computed tomography findings in patients with parathyroid adenomas. | |
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MedLine Citation:
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PMID: 21969785 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Primary hyperparathyroidism results from excessive parathyroid hormone secretion. Approximately 85% of all cases of primary hyperparathyroidism are caused by a single parathyroid adenoma; 10-15% of the cases are caused by parathyroid hyperplasia. Parathyroid carcinoma accounts for approximately 3-4% of cases of primary disease. Technetium-99m-sestamibi (MIBI), the current scintigraphic procedure of choice for preoperative parathyroid localization, can be performed in various ways. The "single-isotope, double-phase technique" is based on the fact that MIBI washes out more rapidly from the thyroid than from abnormal parathyroid tissue. However, not all parathyroid lesions retain MIBI and not all thyroid tissue washes out quickly, and subtraction imaging is helpful. Single photon emission computed tomography (SPECT) provides information for localizing parathyroid lesions, differentiating thyroid from parathyroid lesions, and detecting and localizing ectopic parathyroid lesions. Addition of CT with SPECT improves the sensitivity. This pictorial assay demonstrates various SPECT/CT patterns observed in parathyroid scintigraphy. |
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Authors:
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Dhritiman Chakraborty; Bhagwant Rai Mittal; Chidambaram Natrajan Balasubramanian Harisankar; Anish Bhattacharya; Sanjay Bhadada |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India Volume: 26 ISSN: 0974-0244 ISO Abbreviation: Indian J Nucl Med Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-10-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8901274 Medline TA: Indian J Nucl Med Country: India |
Other Details:
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Languages: eng Pagination: 52-5 Citation Subset: - |
Affiliation:
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Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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