Document Detail

Spectrum of cytomorphological features, including literature review, of an extraskeletal myxoid chondrosarcoma with t(9;22)(q22;q12) (TEC/EWS) results in one case.
MedLine Citation:
PMID:  18925568     Owner:  NLM     Status:  MEDLINE    
Extraskeletal myxoid chondrosarcoma (EMC) is an uncommon soft tissue sarcoma with evolving literature on its cytomorphological features and limited documentation of its molecular analysis. Herein, we present cytological features, including review, of four cases of an EMC. Smears were predominantly hypercellular, comprising tumor cells arranged in clusters, traberculae, and cords against a variable chondromyxoid background. Cells were mainly polygonal shaped with round to indented nuclei, uniform chromatin, displaying intranuclear inclusions, grooves, and eosinophilic to finely vacuolated cytoplasm. Three cases revealed presence of "rhabdoid" cells. All cases had histopathologic confirmation. One case displayed t(9;22)(q22;q12) translocation by fluorescent in situ hybridization (FISH), on smears.
Rajiv Kumar; Bharat Rekhi; Nadia Shirazi; Anurita Pais; Pratibha Amare; Deepali Gawde; Nirmala Jambhekar
Related Documents :
6247458 - Lateral horn cells in progressive autonomic failure.
16341628 - Xanthogranuloma of the sellar region.
3573898 - Polymorphous low-grade adenocarcinoma of the tongue.
7868088 - Mesothelial cell inclusions within mediastinal lymph nodes.
25204708 - Clinical manifestations of igg4-related disease in the pharynx: case series and review ...
24715798 - The genus micatagla argaman, 1994 in egypt, with three new species and a new record (hy...
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Diagnostic cytopathology     Volume:  36     ISSN:  1097-0339     ISO Abbreviation:  Diagn. Cytopathol.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-12     Completed Date:  2009-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506895     Medline TA:  Diagn Cytopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  868-75     Citation Subset:  IM    
Copyright Information:
(c) 2008 Wiley-Liss, Inc.
Department of Pathology, Tata Memorial Hospital, India.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bone Neoplasms / genetics,  pathology*
Chondrosarcoma / genetics,  pathology*
Chromosomes, Human, Pair 22 / genetics*
Chromosomes, Human, Pair 9 / genetics*
Diagnosis, Differential
Middle Aged
RNA-Binding Protein EWS / genetics*
Translocation, Genetic*
Reg. No./Substance:
0/RNA-Binding Protein EWS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Fine-needle aspiration biopsy of thyroid nodules as a possible source for molecular studies: analysi...
Next Document:  Ovarian carcinoma presenting with axillary lymph node metastasis: a case diagnosed by fine-needle as...