| Spectrum of cardiac involvement in neonatal lupus. | |
| | |
MedLine Citation:
|
PMID: 20696015 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
'Neonatal' lupus erythematosus (NLE) describes a clinical spectrum of cardiac and non-cardiac abnormalities observed in neonates and foetuses whose mothers have the auto-antibodies anti-SSA/Ro (anti-Ro) and anti-SSB/La (anti-La). Of the cardiac abnormalities, congenital AVB is the most common cardiovascular abnormality found in affected foetuses and infants. Many other cardiovascular manifestations of NLE have been more recently recognized including atrial and ventricular arrhythmias and other conduction abnormalities, myocarditis, cardiomyopathy often with endocardiofibroelastosis and structural heart disease, particularly valvar lesions. In this report, the spectrum of cardiovascular manifestations observed in foetuses and infants with NLE are reviewed and the pathogenesis, diagnosis and clinical outcomes are briefly discussed. |
| | |
Authors:
|
L K Hornberger; N Al Rajaa |
Related Documents
:
|
2460845 - An autopsy case of congenital complete heart block in a newly born of a mother with sys... 8023205 - Congenital heart disease in infants with down's syndrome. 3618495 - Echocardiographic versus cardiac catheterization diagnosis of infants with congenital h... 58975 - Brain changes in newborns, infants and children with congenital heart disease in associ... 7115635 - Ritodrine in the management of fetal distress. 3964585 - Facilitators and regulators: conscious and unconscious processes in pregnancy and early... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Scandinavian journal of immunology Volume: 72 ISSN: 1365-3083 ISO Abbreviation: Scand. J. Immunol. Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-08-10 Completed Date: 2010-10-21 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0323767 Medline TA: Scand J Immunol Country: England |
Other Details:
|
Languages: eng Pagination: 189-97 Citation Subset: IM |
Affiliation:
|
Fetal & Neonatal Cardiology Program, Division of Cardiology, Department of Pediatrics, Stollery Children's Hospital, Women's & Children's Health Research Institute, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada. lisa.hornberger@albertahealthservices.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Arrhythmias, Cardiac
/
congenital,
etiology,
pathology,
physiopathology Atrioventricular Block / congenital, etiology, immunology, pathology, physiopathology Cardiomyopathies / congenital, etiology, immunology, pathology, physiopathology Heart Diseases / congenital, etiology*, immunology, pathology, physiopathology Humans Infant, Newborn Infant, Newborn, Diseases / etiology*, immunology, pathology, physiopathology Lupus Erythematosus, Systemic / complications*, congenital*, immunology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Autoantibodies associated with congenital heart block.
Next Document: Arrhythmias presenting in neonatal lupus.