Document Detail


The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection.
MedLine Citation:
PMID:  21367734     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For individuals with human immunodeficiency virus (HIV) infection to fully benefit from potent combination antiretroviral therapy, they need to know that they are HIV infected, be engaged in regular HIV care, and receive and adhere to effective antiretroviral therapy. Test-and-treat strategies for HIV prevention posit that expanded testing and earlier treatment of HIV infection could markedly decrease ongoing HIV transmission, stemming the HIV epidemic. However, poor engagement in care for HIV-infected individuals will substantially limit the effectiveness of test-and-treat strategies. We review the spectrum of engagement in care for HIV-infected individuals in the United States and apply this information to help understand the magnitude of the challenges that poor engagement in care will pose to test-and-treat strategies for HIV prevention.
Authors:
Edward M Gardner; Margaret P McLees; John F Steiner; Carlos Del Rio; William J Burman
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  52     ISSN:  1537-6591     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-03     Completed Date:  2011-06-07     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  793-800     Citation Subset:  IM    
Affiliation:
Denver Public Health, Denver, Colorado, USA. edward.m.gardner@dhha.org
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MeSH Terms
Descriptor/Qualifier:
Anti-HIV Agents / therapeutic use*
Antiretroviral Therapy, Highly Active / methods*
HIV Infections / diagnosis*,  drug therapy,  prevention & control*
Humans
Patient Acceptance of Health Care / statistics & numerical data*
United States
Grant Support
ID/Acronym/Agency:
K01 AI067063/AI/NIAID NIH HHS; R34 MH090870/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
0/Anti-HIV Agents
Comments/Corrections
Comment In:
Clin Infect Dis. 2011 Mar 15;52(6):801-2   [PMID:  21367735 ]
Clin Infect Dis. 2011 Dec;53(11):1168-9; author's reply 1169-70   [PMID:  21976466 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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