| Spectral Doppler waveforms in systemic arteries and physiological significance of a patent ductus arteriosus. | |
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MedLine Citation:
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PMID: 20651695 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Patent ductus arteriosus in extremely premature babies is associated with major neonatal morbidities, such as necrotizing enterocolitis and intraventricular hemorrhage. This may be attributable, at least in part, to systemic hypoperfusion secondary to ductal steal. A hemodynamically significant ductus arteriosus (HSDA) is known to be associated with altered systemic blood flow and end-organ hypoperfusion. Although descending aorta blood flow profiles may show abnormal diastolic retrograde flow, Doppler studies of blood flow in the systemic arteries may help improve our understanding of the relationship of a HSDA with these morbidities. In this article, we discuss aspects of diastolic blood flow reversal in the systemic arteries in premature infants with a hemodynamically significant duct. Whether these hemodynamic effects are significant enough to form the basis for initiating treatment is still unclear; these should form the basis for prospective studies. |
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Authors:
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A Sehgal; P Coombs; K Tan; P J McNamara |
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Publication Detail:
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Type: Journal Article Date: 2010-07-22 |
Journal Detail:
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Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 31 ISSN: 1476-5543 ISO Abbreviation: J Perinatol Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 150-6 Citation Subset: IM |
Affiliation:
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1] Monash Newborn, Monash Children's, Monash Medical Centre, Melbourne, VIC, Australia [2] Monash University, Melbourne, VIC, Australia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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