Document Detail


Speckled lentiginous nevus syndrome: report of a further case.
MedLine Citation:
PMID:  15459538     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 42-year-old man had a large speckled lentiginous nevus on the left side of his trunk. The involved area was painful when touched and paresthetic. Moreover, the ipsilateral half of his body showed a pronounced hyperhidrosis. This case can be categorized as a typical example of speckled lentiginous nevus syndrome, a recently recognized phenotype characterized by a speckled lentiginous nevus of the papular type and ipsilateral neurological abnormalities in the form of dysesthesia, muscular weakness or hyperhidrosis. Speckled lentiginous nevus syndrome represents a mosaic phenotype. Most likely it originates from loss of heterozygosity occurring in a heterozygous embryo at an early developmental stage.
Authors:
Claudia Vente; Christine Neumann; Hans Bertsch; Rainer Rupprecht; Rudolf Happle
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Dermatology (Basel, Switzerland)     Volume:  209     ISSN:  1018-8665     ISO Abbreviation:  Dermatology (Basel)     Publication Date:  2004  
Date Detail:
Created Date:  2004-10-01     Completed Date:  2004-12-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9203244     Medline TA:  Dermatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  228-9     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Georg August University, Göttingen, Germany.
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MeSH Terms
Descriptor/Qualifier:
Adult
Humans
Hyperhidrosis / complications
Male
Neurocutaneous Syndromes / diagnosis*,  pathology
Nevus, Pigmented / diagnosis*,  pathology
Skin Neoplasms / diagnosis*,  pathology
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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