Document Detail

Specificity of a human leukocyte neutral proteinase with bovine parathyroid hormone as substrate.
MedLine Citation:
PMID:  6381164     Owner:  NLM     Status:  MEDLINE    
A neutral proteinase, located on the surface of human granulocytes and lymphocytes, degraded bovine parathyroid hormone in vitro. The observed sites of cleavage were between residues 5 and 6 (--ile--gln--), 8 and 9 (--met--his--), 38 and 39 (--gly--ala--) and 41 and 42 (--ile--ala--). Possible physiological implications of these findings are discussed.
P M Barling; K Cartmell; G K Scott
Related Documents :
9204574 - New caerin antibacterial peptides from the skin glands of the australian tree frog lito...
3335534 - Divergence in primary structure between the molecular forms of acetylcholinesterase.
2777784 - Purification and characterization of trehalase inhibitor from hemolymph of the american...
8513794 - Amino acid sequence of the human intermediate basic protein 2 (hpi2) from sperm nuclei....
19668864 - Rna aptamers selected against amyloid beta-peptide (abeta) inhibit the aggregation of a...
10585434 - Self-association of the alpha subunit of phosphorylase kinase as determined by two-hybr...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The International journal of biochemistry     Volume:  16     ISSN:  0020-711X     ISO Abbreviation:  Int. J. Biochem.     Publication Date:  1984  
Date Detail:
Created Date:  1984-10-09     Completed Date:  1984-10-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0250365     Medline TA:  Int J Biochem     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  815-21     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amino Acid Sequence
Amino Acids / analysis
Chromatography, Gel
Chromatography, High Pressure Liquid
Endopeptidases / blood*
Leukocytes / enzymology*
Parathyroid Hormone / metabolism*
Peptide Fragments / analysis
Substrate Specificity
Reg. No./Substance:
0/Amino Acids; 0/Parathyroid Hormone; 0/Peptide Fragments; EC 3.4.-/Endopeptidases; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Kinin-inactivating endopeptidase from rat liver.
Next Document:  Efficacy of low-dose captopril given twice daily to patients with essential hypertension uncontrolle...