Document Detail


Specific staining of glycine N-methyltransferase.
MedLine Citation:
PMID:  8586061     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Glycine N-methyltransferase from rabbit, human, rat and pig livers was separated by isoelectric focusing and a specific functional staining method was developed through the detection of sarcosine produced from the methylation of glycine. Isozyme patterns obtained in the various species tested differ both in the number of bands and apparent isoelectric points. These differences may explain the contradictory data on the subunit structure and glycosylation status of the enzyme reported so far.
Authors:
F Santos; A Amorim; J Kömpf
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Electrophoresis     Volume:  16     ISSN:  0173-0835     ISO Abbreviation:  Electrophoresis     Publication Date:  1995 Oct 
Date Detail:
Created Date:  1996-03-22     Completed Date:  1996-03-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8204476     Medline TA:  Electrophoresis     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  1898-9     Citation Subset:  IM    
Affiliation:
Instituto de Antropologia, Faculdade de Ciências, Universidade do Porto, Portugal.
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MeSH Terms
Descriptor/Qualifier:
Animals
Glycine / metabolism
Glycine N-Methyltransferase
Humans
Isoelectric Focusing / methods*
Isoenzymes / isolation & purification*,  metabolism
Liver / enzymology*
Methylation
Methyltransferases / isolation & purification*,  metabolism
Rabbits
Rats
Sarcosine / analysis,  metabolism
Staining and Labeling*
Swine
Chemical
Reg. No./Substance:
0/Isoenzymes; 107-97-1/Sarcosine; 56-40-6/Glycine; EC 2.1.1.-/Methyltransferases; EC 2.1.1.20/Glycine N-Methyltransferase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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