Document Detail

Specific production of prostaglandin E by human amnion in vitro.
MedLine Citation:
PMID:  635226     Owner:  NLM     Status:  MEDLINE    
Prostaglandin production by intra-uterine human tissues has been investigated using a method of tissue superfusion. Tissues were obtained at elective Caesarean section and after spontaneous vaginal delivery. It was found that all the tissues studied (amnion, chorion, decidua and placenta) produced more prostaglandin E (PGE) and 13,14-dihydro-15-keto-prostaglandin F (PGFM - the major circulating metabolite of prostaglandin F) than prostaglandin F (PGF). Amnion produced significantly more PGE (but not PGF or PGFM) than any other tissue. Prostaglandin production by each tissue was similar whether it was taken at elective Caesarean section or after spontaneous vaginal delivery.
M D Mitchell; J Bibby; B R Hicks; A C Turnbull
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Prostaglandins     Volume:  15     ISSN:  0090-6980     ISO Abbreviation:  Prostaglandins     Publication Date:  1978 Feb 
Date Detail:
Created Date:  1978-05-17     Completed Date:  1978-05-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0320271     Medline TA:  Prostaglandins     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  377-82     Citation Subset:  IM    
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MeSH Terms
Amnion / metabolism*
Cesarean Section
Chorion / metabolism
Decidua / metabolism
Labor, Obstetric
Placenta / metabolism
Prostaglandins E / biosynthesis*
Prostaglandins F / biosynthesis
Reg. No./Substance:
0/Prostaglandins E; 0/Prostaglandins F

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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