Document Detail


Specific determination and identification of cross-linked fibrin degradation products in patients under thrombolytic therapy for myocardial infarction.
MedLine Citation:
PMID:  3114888     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We have demonstrated that the specific determination and identification of plasma FbDP alone is not sufficient to follow the effectiveness of thrombolytic therapy. Some patients who received an intravenous infusion of rt-PA for myocardial infarction had very high plasma FbDP levels, although no recanalization was observed angiographically. Since in many cases the FbDP levels increased after recanalization, it is assumed that rethrombosis may occur during and after t-PA treatment.
Authors:
J Soria; C Soria; M Mirshahi; M Xi; M Mirshahi; M M Samama; J P Caen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in thrombosis and hemostasis     Volume:  13     ISSN:  0094-6176     ISO Abbreviation:  Semin. Thromb. Hemost.     Publication Date:  1987 Apr 
Date Detail:
Created Date:  1987-10-07     Completed Date:  1987-10-07     Revised Date:  2006-03-07    
Medline Journal Info:
Nlm Unique ID:  0431155     Medline TA:  Semin Thromb Hemost     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  223-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Monoclonal / diagnostic use
Antibody Specificity
Collodion
Electrophoresis, Polyacrylamide Gel
Fibrin Fibrinogen Degradation Products / analysis*
Fibrinolytic Agents / pharmacology,  therapeutic use*
Humans
Infusions, Intravenous
Methods
Myocardial Infarction / blood,  drug therapy*
Protein Conformation
Recombinant Proteins / administration & dosage,  therapeutic use
Sodium Dodecyl Sulfate
Tissue Plasminogen Activator / administration & dosage,  therapeutic use
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Fibrin Fibrinogen Degradation Products; 0/Fibrinolytic Agents; 0/Recombinant Proteins; 151-21-3/Sodium Dodecyl Sulfate; 9004-70-0/Collodion; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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