| Specific changes in the in vitro production of prostanoids by the ovine cervix at parturition. | |
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MedLine Citation:
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PMID: 7384553 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A method of tissue superfusion has been used to measure in vitro prostanoid production by the ovine cervix during late pregnancy and at parturition. In late pregnancy (105-135 days of gestation) cervical tissue produced relatively large amounts of prostaglandin E (PGE); in comparison, the production rates of prostaglandin F (PGF), 13, 14-dihydro-15-oxo-prostaglandin F (PGFM) and 6-oxo-prostaglandin F1 alpha were generally low. Thromboxane B2 (TXB2) production was minimal and often unmeasurable. There were significant increases in the production rates of PGE and 6-oxo-PGF1 alpha by cervical tissue taken immediately after delivery, when compared to late pregnancy. Mean production rates of PGE increased from 19.8 +/- 4.1 to 43.8 +/- 7.4 ng/g. dry wt./min; 6-oxo-PGF1 alpha production rates increased more than three-fold from 10.0 +/- 2.7 to 34.6 +/- 9.8 ng/g. dry wt./min (means +/- S.E.M.). There were no significant differences in the rates of production of PGF, PGFM and TXB2 by the two groups. |
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Authors:
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D A Ellwood; M D Mitchell; A B Anderson; A C Turnbull |
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12962953 - Cervical cerclage for prevention of preterm delivery: meta-analysis of randomized trials. 8690283 - Benign cervical leiomyoma leading to disseminated fatal malignancy. 1738523 - Placental compressibility: implications for indirect diagnosis of posterior placenta pr... |
Publication Detail:
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Type: Comparative Study; In Vitro; Journal Article |
Journal Detail:
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Title: Prostaglandins Volume: 19 ISSN: 0090-6980 ISO Abbreviation: Prostaglandins Publication Date: 1980 Mar |
Date Detail:
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Created Date: 1980-08-28 Completed Date: 1980-08-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0320271 Medline TA: Prostaglandins Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 479-88 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cervix Uteri / metabolism* Female Labor, Obstetric* Perfusion Pregnancy Prostaglandins / biosynthesis* Prostaglandins E / biosynthesis Prostaglandins F / biosynthesis Sheep / metabolism Thromboxane B2 / biosynthesis |
| Chemical | |
Reg. No./Substance:
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0/Prostaglandins; 0/Prostaglandins E; 0/Prostaglandins F; 54397-85-2/Thromboxane B2 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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