Document Detail

Specific IgE antibodies to aeroallergens and food among Israelis.
MedLine Citation:
PMID:  10480589     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: There are no data about specific IgE antibodies to food and aeroallergens in the Israeli population.
OBJECTIVE: We sought to determine the relationship between selected demographic parameters and rate of sensitivity to various allergens throughout all ages.
METHODS: Analysis was carried out on 776 positive specific IgE from 655 patients (347 to food, 429 to aeroallergens, and 121 to both). The studied parameters were age and gender.
RESULTS: Age-related analysis showed the highest positivity to food (eggs, legumes, and milk) and the lowest to pollens during infancy. High sensitivity to house mites prevailed at all ages. Sensitivity to pollens and epidermals increased with age while sensitivity to eggs, legumes, and milk decreased. Above the age of 30 years, the rate of sensitivity to all tested aeroallergens and food was similar and close to the average value. Our data showed a significant cross-sensitivity between various foods and aeroallergens and also confirmed cross-sensitivity results reported earlier.
CONCLUSIONS: (1) Age is a dominant factor affecting type I hypersensitivity. House mite is the most common allergen throughout life. (2) The age distribution and nature of sensitivity to allergens in Israel has some similarities to Spain but differ from other countries. (3) Cross-sensitivity between food and aeroallergens was found.
Y Kornizky; M Topilsky; E Fireman; S Kivity; S Kivity
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology     Volume:  83     ISSN:  1081-1206     ISO Abbreviation:  Ann. Allergy Asthma Immunol.     Publication Date:  1999 Aug 
Date Detail:
Created Date:  1999-10-06     Completed Date:  1999-10-06     Revised Date:  2013-01-18    
Medline Journal Info:
Nlm Unique ID:  9503580     Medline TA:  Ann Allergy Asthma Immunol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  149-52     Citation Subset:  IM    
Department of Internal Medicine H, Tel Aviv University, Israel.
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MeSH Terms
Air Pollution*
Allergens / immunology*
Antibodies, Anti-Idiotypic / immunology*
Antibody Specificity
Child, Preschool
Food Hypersensitivity / epidemiology*,  immunology*
Fruit / immunology
Immunoglobulin E / immunology
Infant, Newborn
Israel / epidemiology
Radioallergosorbent Test
Sex Ratio
Vegetables / immunology
Reg. No./Substance:
0/Allergens; 0/Antibodies, Anti-Idiotypic; 0/anti-IgE antibodies; 37341-29-0/Immunoglobulin E

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