Document Detail


Specific Detection of d-Glucose by a Tetraphenylethene-Based Fluorescent Sensor.
MedLine Citation:
PMID:  21171593     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A conceptually new "light-up" biosensor with a high specificity for d-glucose (Glu) in aqueous media has been developed. The emission from a tetraphenylethene (TPE)-cored diboronic acid (1) was greatly boosted when the fluorogen was oligomerized with Glu because of restriction of the intramolecular rotations of the aryl rotors of TPE by formation of the oligomer. Little change in the light emission was observed when 1 was mixed with d-fructose, d-galactose, or d-mannose, as these saccharides are unable to oligomerize with the fluorogen.
Authors:
Yi Liu; Chunmei Deng; Li Tang; Anjun Qin; Rongrong Hu; Jing Zhi Sun; Ben Zhong Tang
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Publication Detail:
Type:  Journal Article     Date:  2010-12-20
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  133     ISSN:  1520-5126     ISO Abbreviation:  J. Am. Chem. Soc.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  660-3     Citation Subset:  IM    
Affiliation:
Institute of Biomedical Macromolecules, Department of Polymer Science and Engineering, MoE Key Laboratory of Macromolecule Synthesis and Functionalization, Zhejiang University , Hangzhou 310027, China.
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