Document Detail

Species-specific non-expression of ribosomal RNA genes in a mammalian hybrid, the mule.
MedLine Citation:
PMID:  3829827     Owner:  NLM     Status:  MEDLINE    
The expression of nucleolus organizer activity in diploid cells was investigated in a model system for mammalian hybrids, the horse-ass cross (mule), by means of sequential Ag-NOR and chromomycin A3/distamycin A-DAPI (CDD) staining in lectin-stimulated peripheral blood lymphocytes (PBL). As a rule we found species-specific non-expression of the horse-derived NOR chromosomes in the mule, whereas the ass-derived NOR chromosomes were active. The results of PBL interphase studies were compatible with the data gained from mitotic metaphase analyses.
E Kopp; B Mayr; W Schleger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chromosoma     Volume:  94     ISSN:  0009-5915     ISO Abbreviation:  Chromosoma     Publication Date:  1986  
Date Detail:
Created Date:  1987-05-11     Completed Date:  1987-05-11     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  2985138R     Medline TA:  Chromosoma     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  346-52     Citation Subset:  IM    
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MeSH Terms
Chromosome Mapping
DNA, Ribosomal / metabolism*
Gene Expression Regulation*
Hybridization, Genetic*
Nucleolus Organizer Region / ultrastructure*
Perissodactyla / genetics*
RNA, Ribosomal / biosynthesis*
Species Specificity
Reg. No./Substance:
0/DNA, Ribosomal; 0/RNA, Ribosomal

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