Document Detail


Species identification and vitamin A level in lutjanid fish implicated in vitamin A poisoning.
MedLine Citation:
PMID:  20377970     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One outbreak of food poisoning associated with ingestion of the liver of a large lutjanid fish was investigated in this study. The symptoms in three patients primarily included headache, nausea, vomiting, fever, vertigo, and visual disorientation and later included peeling of the skin. The species of fish implicated in this incident was Etelis carbunculus (family Lutjanidae) as determined by direct sequence analysis and PCR plus restriction fragment length polymorphism analysis for detection of the cytochrome b gene. Subsequently, several specimens of E. carbunculus of different body weights were collected, and the level of vitamin A in the muscle and liver was determined by high-performance liquid chromatography. The average level of vitamin A in E. carbunculus muscle was 12 +/- 2 IU/g and that in the liver was 9,844 +/- 7,812 IU/g. Regression models indicate that E. carbunculus with higher body weight and liver weight will have higher levels of vitamin A levels in the liver.
Authors:
Deng-Fwu Hwang; Chi-Huan Lu; Wen-Feng Lin
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of food protection     Volume:  73     ISSN:  0362-028X     ISO Abbreviation:  J. Food Prot.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-09     Completed Date:  2010-05-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703944     Medline TA:  J Food Prot     Country:  United States    
Other Details:
Languages:  eng     Pagination:  769-73     Citation Subset:  IM    
Affiliation:
Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan. dfhwang@mail.tou.edu.tw
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Body Weight
Chromatography, High Pressure Liquid
Consumer Product Safety
Cytochromes b / genetics
DNA / analysis
Female
Food Contamination / analysis*
Foodborne Diseases / etiology
Humans
Hypervitaminosis A / etiology
Liver / chemistry,  metabolism
Male
Muscle, Skeletal / chemistry,  metabolism
Organ Size
Perciformes / genetics,  metabolism*
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Seafood / analysis*
Species Specificity
Vitamin A / analysis*
Chemical
Reg. No./Substance:
11103-57-4/Vitamin A; 9007-49-2/DNA; 9035-37-4/Cytochromes b

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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