Document Detail

Special investigations of COCM: endomyocardial biopsies (morphological analysis).
MedLine Citation:
PMID:  704516     Owner:  NLM     Status:  MEDLINE    
Endomyocardial tissue obtained from 237 patients clinically suspected of suffering from congestive cardiomyopathy, has been analysed histologically, histochemically and ultrastructurally. In 51% of patients, the suspected diagnosis was morphologically confirmed and in 24.5%, no pathological evidence of a dilated heart or other pathology was found. The results in these two groups were considered helpful. It is concluded that, even though the morphology of congestive cardiomyopathy in non-specific and the number of other pathology found is small, the continuation of investigation by bioptome is justified. Parameters such as prognosis and length of history can also be assessed. Furthermore, morphological analysis is essential to interpret accurately biochemical and other types of investigations that are being carried out on biopsy material.
E G Olsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  54     ISSN:  0032-5473     ISO Abbreviation:  Postgrad Med J     Publication Date:  1978 Jul 
Date Detail:
Created Date:  1978-12-20     Completed Date:  1978-12-20     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  486-93     Citation Subset:  IM    
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MeSH Terms
Cardiomyopathies / metabolism,  pathology*
Glycogen / analysis
Microscopy, Electron
Middle Aged
Myocardium / metabolism,  ultrastructure
Succinate Dehydrogenase / analysis
Reg. No./Substance:
9005-79-2/Glycogen; EC Dehydrogenase

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