| Spatial variation of blood viscosity: Modelling using shear fields measured by a μPIV based technique. | |
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MedLine Citation:
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PMID: 20943426 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The spatial characteristics of blood viscosity were investigated by combining a newly developed constitutive equation with shear deformation fields calculated from velocity measurements obtained by a μPIV based technique. Blood at physiological hematocrit levels and in the presence of aggregation was sheared in a narrow gap plate-plate geometry and the velocity and aggregation characteristics were determined from images captured using a high resolution camera. Changes in the microstructure of blood caused by aggregation were observed to affect the flow characteristics. At low shear rates, high aggregation and network formation caused the RBC motion to become essentially two-dimensional. The measured velocity fields were used to estimate the magnitude of shear which was subsequently used in conjunction with the new model to assess the spatial variation of viscosity across the flow domain. It was found that the non-uniform microstructural characteristics of blood influence its viscosity distribution accordingly. The viscosity of blood estimated in the core of the examined flow, using a zero-gradient core velocity profile assumption, was found to be significantly higher than the overall effective viscosity determined using other velocity profile assumptions. |
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Authors:
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Efstathios Kaliviotis; Jonathan Dusting; Stavroula Balabani |
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Publication Detail:
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Type: Journal Article Date: 2010-10-12 |
Journal Detail:
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Title: Medical engineering & physics Volume: 33 ISSN: 1873-4030 ISO Abbreviation: Med Eng Phys Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-08-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9422753 Medline TA: Med Eng Phys Country: England |
Other Details:
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Languages: eng Pagination: 824-31 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 IPEM. Published by Elsevier Ltd. All rights reserved. |
Affiliation:
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Experimental and Computational Laboratory for the Analysis of Turbulence (ECLAT), King's College London, Strand, London WC2R 2LS, United Kingdom. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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