Document Detail


Spatial and temporal patterns of human jejunal contractions.
MedLine Citation:
PMID:  2782412     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We recorded human jejunal motor activity by a 12-lumen manometric tube with recording sites 2 cm apart. The contractile activity in the fasted and the fed state was analyzed by computer to define the spatial and temporal patterns of contractions. Mean duration and area of single contractions during phase III activity were not different from those during phase II activity. By contrast, the frequency and amplitude of contractions, their propagation distance, and the percentage of contractions that propagated for greater than or equal to 2 cm were significantly greater during phase III than during phase II activity. The mean frequency and percentage of propagated contractions in the fed state were intermediate between those during phase II and phase III activity. Mean propagation distance of postprandial contractions was not different from that of phase II contractions. Most contractions in the fed state were uncoordinated at adjacent recording sites. Occasionally, large-amplitude and long-duration contractions, called individual migrating contractions, propagated over long distances and frequently over the entire 22-cm study segment. We conclude that there are some significant differences between the spatial and temporal patterns of contractions between the fed state and phase II and phase III activity. The largely disorganized phasic contractions in the fed state may cause mostly mixing of the ingested meal and its slow distal propagation, whereas the infrequent individual migrating contractions may rapidly propel intestinal contents over longer distances.
Authors:
S K Sarna; K H Soergel; J M Harig; F D Loo; C M Wood; K M Donahue; R P Ryan; R C Arndorfer
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of physiology     Volume:  257     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-10-18     Completed Date:  1989-10-18     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  G423-32     Citation Subset:  IM    
Affiliation:
Department of Surgery, Medical College of Wisconsin, Milwaukee.
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MeSH Terms
Descriptor/Qualifier:
Adult
Fasting
Female
Humans
Jejunum / physiology*
Male
Middle Aged
Muscle Contraction*
Muscles / physiology*
Grant Support
ID/Acronym/Agency:
AM-07267/AM/NIADDK NIH HHS; DK-32346/DK/NIDDK NIH HHS; RR00058/RR/NCRR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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