Document Detail

Spatial and temporal gait parameters in Alzheimer's disease and aging.
MedLine Citation:
PMID:  19740661     Owner:  NLM     Status:  MEDLINE    
Spatial and temporal gait parameters in 40 patients with early Alzheimer's disease (AD) were compared to that of 34 normal controls (NC) on a level ground and on a treadmill. Over-ground velocity, cycle-time, cadence, stride-length, stride-width and double-support time were captured on an electronic walkway. On the treadmill, cadence, cycle-time and double-support time were recorded at a preferred velocity using footswitches. The AD group were significantly slower on the Timed Up and Go task compared to NC (p<0.05). AD patients differed significantly from the NC on their over-ground gait velocity (99+/-19 cm/s vs 119+15 cm/s, p<0.001), cadence (101+/-9 steps/min vs 109+/-9 steps/min, p=0.001) and stride-length (118+/-18 cm vs 131+/-17 cm, p<0.01). On the treadmill, only preferred speed was significantly different in the AD group compared to the NC group (60+/-20 cm/s vs 74+/-23 cm/s, p=0.02). These results indicate that patients with early AD walk slower and with shorter strides than healthy older adults.
Neelesh K Nadkarni; Elysha Mawji; William E McIlroy; Sandra E Black
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-09-08
Journal Detail:
Title:  Gait & posture     Volume:  30     ISSN:  1879-2219     ISO Abbreviation:  Gait Posture     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-09-28     Completed Date:  2010-01-07     Revised Date:  2014-05-27    
Medline Journal Info:
Nlm Unique ID:  9416830     Medline TA:  Gait Posture     Country:  England    
Other Details:
Languages:  eng     Pagination:  452-4     Citation Subset:  IM    
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MeSH Terms
Age Factors
Aged, 80 and over
Aging / physiology*
Alzheimer Disease / physiopathology*
Case-Control Studies
Chi-Square Distribution
Gait Disorders, Neurologic / physiopathology*
Longitudinal Studies
Middle Aged
Task Performance and Analysis
Time Factors
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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