Document Detail


Spatial patterns of fasting and fed antropyloric pressure waves in humans.
MedLine Citation:
PMID:  9306286     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Gastric mechanics were investigated by categorizing the temporal and spatial patterning of pressure waves associated with individual gastric contractions. 2. In twelve healthy volunteers, intraluminal pressures were monitored from nine side hole recording points spaced at 1.5 cm intervals along the antrum, pylorus and duodenum. 3. Pressure wave sequences that occurred during phase II fasting contractions (n = 221) and after food (n = 778) were evaluated. 4. The most common pattern of pressure wave onset along the antrum was a variable combination of antegrade, synchronous and retrograde propagation between side hole pairs. This variable pattern accounted for 42% of sequences after food, and 34% during fasting (P < 0.05). Other common pressure wave sequence patterns were: purely antegrade-29% after food and 42% during fasting (P < 0.05); purely synchronous-23% fed and 17% fasting; and purely retrograde-6% fed and 8% fasting. The length of sequences was shorter after food (P < 0.05). Some sequences 'skipped' individual recording points. 5. The spatial patterning of gastric pressure wave sequences is diverse, and may explain the differing mechanical outcomes among individual gastric contractions. 6. Better understanding of gastric mechanics may be gained from temporally precise correlations of luminal flows and pressures and gastric wall motion during individual gastric contraction sequences.
Authors:
W M Sun; G S Hebbard; C H Malbert; K L Jones; S Doran; M Horowitz; J Dent
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of physiology     Volume:  503 ( Pt 2)     ISSN:  0022-3751     ISO Abbreviation:  J. Physiol. (Lond.)     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-11-19     Completed Date:  1997-11-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0266262     Medline TA:  J Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  455-62     Citation Subset:  IM    
Affiliation:
Department of Medicine, Royal Adelaide Hospital, University of Adelaide, SA, Australia. wmsun@medicine.adelaide.edu.au
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MeSH Terms
Descriptor/Qualifier:
Adult
Duodenum / physiology
Fasting / physiology*
Female
Humans
Male
Middle Aged
Postprandial Period / physiology*
Pressure
Pyloric Antrum / physiology
Pylorus / anatomy & histology,  physiology
Stomach / anatomy & histology,  physiology*
Time Factors
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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