Document Detail


Spatial and frequency differences of neuromagnetic activities in processing concrete and abstract words.
MedLine Citation:
PMID:  18058218     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigated the neuromagnetic spatial and frequency differences between recognizing concrete and abstract words using a 275 channel whole head magnetoencephalography (MEG) system. The stimuli consisted of 100 concrete words and 100 abstract words which were presented visually and auditorily simultaneously. The data of 12 right-handed healthy subjects in six different frequency bands were analyzed with synthetic aperture magnetometry (SAM) which can identify the frequency-dependent volumetric distribution of the evoked magnetic field. Concrete and abstract words evoked a very similar neuromagnetic activation pattern in the primary visual and auditory cortices. However, concrete words evoked stronger synchronization in the right hemisphere and abstract words evoked stronger synchronization in the left hemisphere in 1-8 Hz. In addition, concrete words evoked more desynchronization in the left posterior temporal and parietal cortex; while abstract words evoked a clear synchronization in the left posterior temporal cortex and desynchronization in the left inferior frontal cortex in 70-120 Hz. Furthermore, concrete words evoked clear desynchronization in the left inferior frontal cortex while abstract words evoked strong synchronization in the left posterior temporal cortex in 200-300 Hz. These findings suggested that concrete words and abstract words are processed differently in the brain not only in anatomical substrates, but also in the frequency band of neural activation.
Authors:
Yinhong Liu; Jing Xiang; Yingying Wang; Jennifer J Vannest; Anna W Byars; Douglas F Rose
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Publication Detail:
Type:  Journal Article     Date:  2007-12-06
Journal Detail:
Title:  Brain topography     Volume:  20     ISSN:  0896-0267     ISO Abbreviation:  Brain Topogr     Publication Date:  2008  
Date Detail:
Created Date:  2008-02-07     Completed Date:  2008-05-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8903034     Medline TA:  Brain Topogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  123-9     Citation Subset:  IM    
Affiliation:
Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. liuyh302@126.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain Mapping*
Cerebral Cortex / anatomy & histology,  physiology*
Evoked Potentials, Auditory / physiology*
Evoked Potentials, Visual / physiology*
Female
Frontal Lobe / anatomy & histology,  physiology
Humans
Language*
Magnetics
Magnetoencephalography
Male
Mental Processes / physiology*
Temporal Lobe / anatomy & histology,  physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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