| Spasticity in multiple sclerosis: results of a Spanish patient survey. | |
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MedLine Citation:
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PMID: 23297730 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Information regarding the epidemiology of spasticity in patients with multiple sclerosis (MS) in Spain is limited. This cross-sectional survey-based study was undertaken to evaluate the symptoms, severity and consequences of MS-related spasticity (MSS), and to estimate the prevalence of MSS overall and according to the degree of severity (mild/moderate/severe). Adult MS patients (n = 8463) from the two main Spanish MS patients' associations were asked to complete a web-based questionnaire. 2627 responses were received of which 2029 were valid for analysis. Two-thirds were for women. The mean age of respondents was 40.2 years and the mean MS duration was 8.7 years. MSS was reported by 65.7% of respondents with 40% of these rating it as moderate/severe. MS patients with spasticity experienced more symptoms (including greater difficulty walking), consumed more healthcare resources (including care and rehabilitation sessions), and had a higher degree of disability than patients without spasticity. There was a significant correlation between increasing severity of spasticity and worsening of symptoms. Only 42.4% of patients with moderate spasticity and 52.6% of patients with severe spasticity were currently receiving antispasticity medication compared with 69% and 79%, respectively, reported in a similar survey-based study from the US; this is likely to reflect regional variations in practice. Early and effective treatment of MSS is important to minimise the consequences of spasticity-related symptoms on patients' quality of life and the economic burden on healthcare systems. In appropriate patients, antispastic treatment including pharmacotherapy and physiotherapy/rehabilitation may provide such benefits. An overview of the 6E study was presented as a poster at the 5th Triennial Congress of the European and Americas Committees for Treatment and Research in Multiple Sclerosis (ECTRIMS/ACTRIMS). 19-22 October 2011, Amsterdam, The Netherlands. |
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Authors:
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C Oreja-Guevara; D González-Segura; C Vila |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-9 |
Journal Detail:
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Title: The International journal of neuroscience Volume: - ISSN: 1563-5279 ISO Abbreviation: Int. J. Neurosci. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0270707 Medline TA: Int J Neurosci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Multiple Sclerosis Unit, Neurology, University Hospital San Carlos; IdISSC , Madrid , Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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