Document Detail

Spark source mass spectrographic study of metal allergenic substances on the skin.
MedLine Citation:
PMID:  977988     Owner:  NLM     Status:  MEDLINE    
By spark source mass spectrography it is possible to trace very low concentrations of substances such as chromium, cobalt, and nickel in ethanol extracts of the skin. Chromium could be detected in abnormally high concentrations 3 weeks after one application, while nickel and cobalt reached background levels after 2 to 3 weeks. Touching a door handle containing chromium leads to a significant rise in the chromium content of the skin. Increased chromium content of the skin was evident in one case of wristwatch eczema as well.
O H Christie; N Dinh-Nguyen; J Vincent; L Hellgren; W Pimlott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of investigative dermatology     Volume:  67     ISSN:  0022-202X     ISO Abbreviation:  J. Invest. Dermatol.     Publication Date:  1976 Nov 
Date Detail:
Created Date:  1977-01-03     Completed Date:  1977-01-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0426720     Medline TA:  J Invest Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  587-90     Citation Subset:  AIM; IM    
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MeSH Terms
Allergens / analysis*
Chromium / analysis
Cobalt / analysis
Dermatitis, Atopic / etiology*
Mass Spectrometry
Metals / analysis*
Nickel / analysis
Skin / analysis*
Reg. No./Substance:
0/Allergens; 0/Metals; 7440-02-0/Nickel; 7440-47-3/Chromium; 7440-48-4/Cobalt

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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