Document Detail


Sparing of saphenous vein during inguinal lymphadenectomy for vulval malignancies.
MedLine Citation:
PMID:  17408728     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This work was set out to investigate the effect of saphenous vein preservation during inguinal lymphadenectomy for patients with vulval malignancies. METHODS: 64 patients with vulval malignancies were allocated into two groups depending on their clinical stages, with one of them (31 patients included) being subjected to sparing of saphenous vein and the other to saphenous vein ligated surgery while treated with inguinal lymphadenectomy. The operative time, blood loss, 5-year survival rate, short- and long-term postoperative complications, 5-year survival rate and groin recurrence were selected as the monitored parameters, through which the above two groups were compared with each other using t test, chi2 and life table analysis. RESULTS: (1) The median operative time for bilateral inguinal lymphadenectomy was 155 min (130-170 min) in the sparing group, compared to 140 min (120-170 min) in the excision group (P>0.05). The median intraoperative blood loss was 295 mL (100-450 mL) in the sparing group, and 270 mL (150-390 mL) in the excision group (P>0.05). (2) Short-term lower extremity lymphedema occurred with 27 patients (43.5%) in the sparing group and 44 patients (66.7%) in the excision group (P<0.01). Still, short-term lower extremity phlebitis was observed with 7 patients (11.3%) in the sparing group while 17 developed phlebitis (25.8%) in the excision group (P<0.05). However, there was no statistical difference in postoperative fever, acute cellulites, seroma, or lymphocyst formation. (3) Long-term complication occurrence rate decreased by about 50% in patients subjected to saphenous vein sparing surgery compared with those to ligated surgery, while there was no remarkable difference between two groups in the occurrence rates of phlebitis and deep venous thrombosis (P>0.05). (4) The overall 5-year survival rate was 67.3%, with 66.7% and 68.0% for the excision group and the sparing group, respectively (P>0.05). CONCLUSION: The application of saphenous vein preservation technique during inguinal lymphadenectomy for patients with vulval malignancies could significantly decrease the occurrence rate of postoperative complications without compromising outcomes and should be widely put into clinical practice.
Authors:
Xiaoling Zhang; Xiugui Sheng; Jun Niu; Huiqin Li; Dapeng Li; Ling Tang; Qingshui Li; Qingju Li
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article     Date:  2007-04-03
Journal Detail:
Title:  Gynecologic oncology     Volume:  105     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-21     Completed Date:  2007-06-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  722-6     Citation Subset:  IM    
Affiliation:
Department of Gynecologic Oncology, Shandong Cancer Hospital and Institute, Jinan, 250117, Shandong, PR China.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Loss, Surgical
Female
Humans
Lymph Node Excision / methods*
Lymph Nodes / pathology,  surgery*
Lymphatic Metastasis
Middle Aged
Neoplasm Staging
Saphenous Vein / surgery*
Vulvar Neoplasms / pathology,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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