Document Detail

Spanish language mapping using MEG: a validation study.
MedLine Citation:
PMID:  12414296     Owner:  NLM     Status:  MEDLINE    
The purpose of the present study was to compare magnetoencephalography (MEG) data with the results of the intracarotid amytal procedure (IAP). Twenty-one native Spanish-speaking patients with intractable epilepsy underwent MEG language mapping. A subset of 8 patients also underwent an IAP. With the exception of 2 patients who showed right hemisphere dominance, all other patients showed left hemisphere dominance for language on the MEG recording. The IAP findings were consistent with MEG results in 7 patients. The eighth patient who, according to the MEG data, had probable right hemisphere dominance for language did not show clear hemispheric specialization for language on the IAP and suffered a transient global aphasia following a right temporal lobotomy. These results suggests that MEG-based language mapping can play an important role in presurgical clinical evaluation.
Fernando Maestú; Tomás Ortiz; Alberto Fernandez; Carlos Amo; Pilar Martin; Santiago Fernández; Rafael G Sola
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  NeuroImage     Volume:  17     ISSN:  1053-8119     ISO Abbreviation:  Neuroimage     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-11-04     Completed Date:  2003-02-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9215515     Medline TA:  Neuroimage     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1579-86     Citation Subset:  IM    
Magnetoencephalography Center, Dr. Pérez Modrego, Cognitive Process, Universidad Complutense Madrid, Madrid, Spain.
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MeSH Terms
Amobarbital / diagnostic use
Aphasia / diagnosis,  physiopathology
Brain Mapping*
Dominance, Cerebral / physiology
Electrodes, Implanted
Epilepsy, Temporal Lobe / diagnosis,  physiopathology*,  surgery
Pattern Recognition, Visual / physiology*
Postoperative Complications / diagnosis,  physiopathology
Signal Processing, Computer-Assisted*
Speech Perception / physiology*
Temporal Lobe / physiopathology,  surgery
Reg. No./Substance:

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