| Soy consumption is not protective against diabetes in Hawaii: the Multiethnic Cohort. | |
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MedLine Citation:
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PMID: 20924394 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Based on the hypothesis that soy consumption may improve glucose tolerance, we examined the association of soy intake with diabetes risk in the Hawaii component of the Multiethnic Cohort. Among 29 719 Caucasian, 35 141 Japanese American and 10 484 Native Hawaiian men and women, 8564 incident diabetes cases were identified during 14 years of follow-up. Cox regression was used to calculate hazard ratios while adjusting for known confounders with stratifications by sex, ethnicity and weight status. We observed no protective effect of soy food consumption on diabetes risk in this population, which has a wide range of soy intakes though lower than in Asian populations. Indeed, higher soy food intake was associated with a weakly elevated diabetes risk across ethnic groups; the higher risk was limited to overweight and obese individuals. The current findings do not support a protective effect of modest levels of soy food consumption against diabetes. |
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Authors:
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Y Morimoto; A Steinbrecher; L N Kolonel; G Maskarinec |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. Date: 2010-10-06 |
Journal Detail:
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Title: European journal of clinical nutrition Volume: 65 ISSN: 1476-5640 ISO Abbreviation: Eur J Clin Nutr Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-02-02 Completed Date: 2011-04-22 Revised Date: 2012-01-10 |
Medline Journal Info:
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Nlm Unique ID: 8804070 Medline TA: Eur J Clin Nutr Country: England |
Other Details:
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Languages: eng Pagination: 279-82 Citation Subset: IM |
Affiliation:
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Department of Epidemiology, Cancer Research Center of Hawaii, University of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA. morimoto@crch.hawaii.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Glucose / metabolism Body Weight / physiology* Cohort Studies Diabetes Mellitus, Type 2 / epidemiology, ethnology, prevention & control* Ethnic Groups / statistics & numerical data Female Follow-Up Studies Hawaii Humans Male Middle Aged Risk Factors Soy Foods* |
| Grant Support | |
ID/Acronym/Agency:
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R21 DK073816/DK/NIDDK NIH HHS; R21 DK073816-02/DK/NIDDK NIH HHS; R37 CA054281-18/CA/NCI NIH HHS; R37 CA054281-20/CA/NCI NIH HHS; R37CA54281/CA/NCI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose |
| Comments/Corrections | |
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