| Sources of inhibin in early pregnancy. | |
| | |
MedLine Citation:
|
PMID: 9363237 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Inhibin is a glycoprotein which suppresses the release of follicle stimulating hormone (FSH) from the pituitary. Plasma immunoreactive inhibin levels during pregnancy have been reported to be higher than those during the normal menstrual cycle. In the present study, we investigated the cellular localization of inhibin alpha-, beta A-, and beta B-subunits in the human corpus luteum and placenta during early pregnancy. Luteal cells and theca luteal cells in the corpus luteum of pregnancy exhibited positive staining for all three inhibin subunits. We also observed positive staining with antisera against each inhibin subunit in the syncytiotrophoblast, but not in the cytotrophoblast, in the villi during early pregnancy. The staining with antisera against inhibin alpha- and beta A-subunits was clearly observed, whereas the staining for the beta B-subunit was faint. These results suggest that the gestational corpus luteum and the villous tissue may be major sources of inhibin during early pregnancy. |
| | |
Authors:
|
S Minami; M Yamoto; R Nakano |
Related Documents
:
|
17609507 - Expression of sperm protein 22 (sp22) in the rat ovary during different reproductive st... 9890217 - Haematological effects of betamethasone treatment in late pregnancy. 3653027 - Transuterofetoplacental conversion of pregnenolone to progesterone in antiestrogen-trea... 7530667 - Effect of 5-azacytidine administration during very early pregnancy. 18242817 - Post-voiding residual volume in 154 primiparae 3 days after vaginal delivery under epid... 12635737 - Role of ultrasound evaluation of nuchal translucency in prenatal diagnosis. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Early pregnancy : biology and medicine : the official journal of the Society for the Investigation of Early Pregnancy Volume: 1 ISSN: 1354-4195 ISO Abbreviation: Early Pregnancy Publication Date: 1995 Mar |
Date Detail:
|
Created Date: 1997-12-05 Completed Date: 1997-12-05 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 9508879 Medline TA: Early Pregnancy Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 62-6 Citation Subset: IM |
Affiliation:
|
Department of Obstetrics and Gynecology, Wakayama Medical College, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Corpus Luteum
/
chemistry* Female Humans Immunohistochemistry Inhibins / analysis* Peptides / analysis Placenta / chemistry* Pregnancy Pregnancy Trimester, First Prostatic Secretory Proteins* |
| Chemical | |
Reg. No./Substance:
|
0/Peptides; 0/Prostatic Secretory Proteins; 0/beta-microseminoprotein; 0/inhibin-alpha subunit; 57285-09-3/Inhibins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Insulin-like growth factor-I as a local regulator of proliferation and differentiated function of th...
Next Document: A non-trophoblastic tumor co-existing with a triploid fetus.