Document Detail

Sorbitol adaptation of dental plaque in people with low and normal salivary-secretion rates.
MedLine Citation:
PMID:  2307746     Owner:  NLM     Status:  MEDLINE    
Caries-related bacteriological and biochemical factors were studied in 12 persons with low and 11 persons with normal salivary-secretion rates before and after a four-week period of frequent mouthrinses with 10% sorbitol solution (adaptation period). After the adaptation period, an increase in total numbers of sorbitol-fermenting bacteria and mutans streptococci was found in plaque samples from both groups. The pH drop in dental plaque in situ after a mouthrinse with sorbitol was more pronounced after the adaptation period, especially in the group with the low salivary-secretion rate. Increased acid production in plaque from sorbitol was also observed in the two groups in vitro. The composition of the fermentation end-products was affected by the sorbitol exposure. It is suggested that in subjects with diminished natural protection against caries development, such as patients with low salivary-secretion rate, a cariogenic potential of sorbitol should be considered when this polyol is included in products that might be used frequently.
S Kalfas; G Svensäter; D Birkhed; S Edwardsson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of dental research     Volume:  69     ISSN:  0022-0345     ISO Abbreviation:  J. Dent. Res.     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-04-02     Completed Date:  1990-04-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0354343     Medline TA:  J Dent Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  442-6     Citation Subset:  D; IM    
Department of Oral Microbiology, University of Lund, School of Dentistry, Malmö, Sweden.
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MeSH Terms
Adaptation, Physiological
Colony Count, Microbial
Dental Plaque / metabolism,  microbiology*
Glucose / metabolism
Hydrogen-Ion Concentration
Lactobacillus / isolation & purification,  metabolism*
Middle Aged
Saliva / microbiology
Sorbitol / metabolism*
Streptococcus mutans / isolation & purification,  metabolism*
Xerostomia / physiopathology*
Reg. No./Substance:
0/Mouthwashes; 50-70-4/Sorbitol; 50-99-7/Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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