Document Detail


Sonographic parenchymal and brain perfusion imaging: preliminary results in four patients following decompressive surgery for malignant middle cerebral artery infarct.
MedLine Citation:
PMID:  11295267     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To investigate new methods of diagnostic transcranial sonography for brain parenchymal, vascular and perfusion imaging, we performed 3-D native tissue harmonic transcranial sonography (3D-nthTCS), 3-D transcranial color-coded duplex sonography (3D-TCCS), and "loss-of-correlation" imaging (LOC-TCCS) in four patients following early hemicraniectomy due to space-occupying "malignant" middle cerebral artery infarction (MMCAI). Three-dimensional datasets, utilizing 3D-nthTCS and 3D-TCCS, were created and up to 10 axial 2-D B-mode image planes, similar to CCT, reconstructed in each patient. Three-dimensional reconstructions of the circle of Willis documented one persistent carotid-T occlusion and three recanalizations of the MCA. LOC-TCCS, based on stimulated acoustic emission from an ultrasound (US) contrast agent, demonstrated a perfusion deficit in 2 of 3 patients, with regard to their infarcts. Concluding, 3D-nthTCS, 3D-TCCS and LOC-TCCS are promising tools for bedside monitoring, early prognosis and treatment evaluation for MMCAI in the postoperative period. Further studies should be performed to standardize these new methods and evaluate their applications through the intact calvarina.
Authors:
F Schlachetzki; T Hoelscher; U Dorenbeck; B Greiffenberg; J Marienhagen; O W Ullrich; U Bogdahn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  27     ISSN:  0301-5629     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-04-11     Completed Date:  2001-07-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  21-31     Citation Subset:  IM    
Affiliation:
Department of Neurology, University of Regensburg, Regensburg, Germany. felix.schlachetzki@klinik.uni-regensburg.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Cerebral Infarction / surgery,  ultrasonography*
Cerebrovascular Circulation
Contrast Media / administration & dosage
Craniotomy
Female
Humans
Imaging, Three-Dimensional
Male
Middle Aged
Polysaccharides / administration & dosage
Ultrasonography, Doppler, Transcranial / methods*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Polysaccharides; 127279-08-7/SHU 508

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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