| Sonographic measurements of fetal parts to predict pulmonary maturity among twins and singletons. | |
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MedLine Citation:
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PMID: 10731727 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine if sonographic examination of fetus can be readily utilized to predict a mature lecithin/sphingomyelin (L/S) ratio among twins and singletons. Twins (n = 36) undergoing amniocentesis for assessment of pulmonary maturity were matched with singleton (1:2) for maternal demographics, gestational age (GA), and indications for procedure. At the time of amniocentesis, twins and singletons with mature L/S ratios differed significantly in mean GA (33.2 +/- 2.7 vs 34.5 +/- 4.6 wks, p = 0.01), biparietal diameter (BPD), abdominal circumference (AC), femur length (FL) and estimate of birth weight (EFW). Based on ten receiver operating characteristics curves constructed, the following diagnostic thresholds predicted a mature L/S ratio with a true positive rate of 100% among twins and singletons, respectively: 1) BPD $84 and $92 mm; 2) head circumference $315 and $320 mm; 3) AC $295 and $350 mm; or 4) FL $64 and $72 mm; or 5) EFW $2400 and $3200 g. Using any one of these five criteria correctly identified pulmonary maturity among 59% of twins and 28% of singletons (p = 0.001). Sonographic measurement of fetal parts or EFW may be a noninvasive method to predict a mature L/S ration among twins as well as singletons. |
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Authors:
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S P Chauhan; E F Magann; J C Morrison; A D Gunter; N S Whitworth; L D Devoe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the Mississippi State Medical Association Volume: 41 ISSN: 0026-6396 ISO Abbreviation: J Miss State Med Assoc Publication Date: 2000 Mar |
Date Detail:
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Created Date: 2000-04-07 Completed Date: 2000-04-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7505622 Medline TA: J Miss State Med Assoc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 516-20 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Maternal Fetal Medicine, Medical College of Georgia, Augusta, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biometry Female Femur / embryology Fetal Organ Maturity Gestational Age Humans Lung / embryology* Phosphatidylcholines / analysis Pregnancy ROC Curve Sphingomyelins / analysis Twins* Ultrasonography, Prenatal* |
| Chemical | |
Reg. No./Substance:
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0/Phosphatidylcholines; 0/Sphingomyelins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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