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Sonographic findings in Nicolau syndrome following intramuscular diclofenac injection: A case report.
MedLine Citation:
PMID:  20848573     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Nicolau syndrome (also known as embolia cutis medicamentosa and livedoid dermatitis) is a rare but severe localized adverse drug reaction of intramuscular injection of various drugs. The typical presentation is pain around the injection site soon after injection, followed by erythema, livedoid patch, hemorrhagic patch, and finally necrosis of skin, subcutaneous fat, and muscle tissue. We report a case that occurred in a 34-year-old woman after intramuscular injection of diclofenac sodium. Sonography showed diffuse thickening with increased echogenicity of the skin and subcutaneous fat layer, while MRI revealed extensive edema involving gluteal and piriformis muscles and deep fascia, and fluid collection.
Authors:
Hee-Jin Park; Mi-Sung Kim; Noh-Hyuk Park; Sang-Won Jung; Sung-Il Park; Chan-Sub Park
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Publication Detail:
Type:  Journal Article     Date:  2010-09-16
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  39     ISSN:  1097-0096     ISO Abbreviation:  J Clin Ultrasound     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  United States    
Other Details:
Languages:  eng     Pagination:  111-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Wiley Periodicals, Inc.
Affiliation:
Department of Radiology, Myoungji Hospital, Kwandong University College of Medicine, Koyang, Kyunggido 412-270, Korea.
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