Document Detail


Sonographic atypical vascular coiling of the umbilical cord.
MedLine Citation:
PMID:  15662669     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate whether an atypical umbilical coiling pattern at prenatal sonography is associated with adverse pregnancy outcome. METHODS: A targeted sonographic evaluation of the umbilical cord (UC) was performed in 758 women with singleton gestation, and gestational age above 20 weeks. Atypical coiling was defined as the presence of a spring-shape UC (supercoiling) or an unusual, aperiodic coiling pattern (uncoordinated coiling). Umbilical artery Doppler assessment was conducted in cases with atypical coiling. Pregnancy and neonatal outcomes were investigated. RESULTS: Of the study population, 7 and 16 fetuses had an umbilical cord with uncoordinated coiling and supercoiling respectively. Three umbilical cords had a single umbilical artery. Eight patients delivered before 34 weeks of gestation. Eight fetuses were growth restricted. In seven cases, abnormal sonographic findings were detected (three meconium peritonitis, two severe hydronephrosis and two cardiac anomalies). One fetus affected by trisomy 18 presented multiple anomalies. Perinatal death occurred in three cases. Of the surviving newborns, eight were admitted to NICU. Umbilical artery Doppler waveforms presented a systolic notch in seven (30.4%) cases. CONCLUSIONS: The presence of an atypical umbilical cord vascular coiling is associated with an increased risk of unfavourable pregnancy outcome. The identification of an umbilical artery notch at Doppler investigation is frequently associated with an atypical UC coiling pattern.
Authors:
Antonella Cromi; Fabio Ghezzi; Peter Duerig; Marco Travaglini; Marco Buttarelli; Luigi Raio
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  25     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-31     Completed Date:  2005-04-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  England    
Other Details:
Languages:  eng     Pagination:  1-6     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2005 John Wiley & Sons, Ltd.
Affiliation:
Department of Obstetrics and Gynecology, University of Insubria - F. Del Ponte Hospital, Varese, Italy. antonellacromi@libero.it
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Flow Velocity
Female
Fetal Growth Retardation / ultrasonography
Gestational Age
Humans
Infant, Newborn
Infant, Small for Gestational Age
Placental Circulation
Pregnancy
Ultrasonography, Doppler*
Ultrasonography, Prenatal*
Umbilical Arteries / abnormalities,  ultrasonography
Umbilical Cord / blood supply*,  ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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