| Sonodynamic and photodynamic therapy in advanced breast carcinoma: a report of 3 cases. | |
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MedLine Citation:
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PMID: 19815599 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Photodynamic therapy (PDT) is an established therapeutic method, first approved by the FDA for certain kinds of cancer in 1998. There are also increasing data to show that a related procedure, sonodynamic therapy (SDT), is a promising new modality for cancer treatment. Here, the authors report clinical results in 3 advanced refractory breast cancer patients who were treated using a combination of sonodynamic and photodynamic therapy (SPDT), along with conventional therapies. All 3 patients had pathologically proven metastatic breast carcinoma. These widely disseminated carcinomas had ultimately failed to respond to conventional therapy. A new sensitizing agent, Sonoflora 1 (SF1) was administered sublingually; then, after a 24-hour delay, patients were treated with a combination of light and ultrasound. All patients had significant partial or complete responses. SPDT is a promising new therapeutic combination for the treatment of breast cancer. |
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Authors:
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Xiaohuai Wang; Weimin Zhang; Zhiyong Xu; Yifan Luo; Doug Mitchell; Ralph W Moss |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Integrative cancer therapies Volume: 8 ISSN: 1552-695X ISO Abbreviation: Integr Cancer Ther Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-10-09 Completed Date: 2010-03-12 Revised Date: 2010-12-10 |
Medline Journal Info:
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Nlm Unique ID: 101128834 Medline TA: Integr Cancer Ther Country: United States |
Other Details:
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Languages: eng Pagination: 283-7 Citation Subset: IM |
Affiliation:
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Chemistry and Environment College, Southern China Normal University, Guangzhou, People's Republic of China. wangxhgz@163.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Sublingual Adult Breast Neoplasms / diagnosis, pathology, therapy* Carcinoma / diagnosis, pathology, therapy* Chlorophyll / analogs & derivatives, therapeutic use Combined Modality Therapy / methods Complementary Therapies / instrumentation, methods* Fatal Outcome Female Humans Middle Aged Neoplasm Metastasis / diagnosis, pathology, therapy Photochemotherapy / instrumentation, methods* Photosensitizing Agents / administration & dosage, therapeutic use Positron-Emission Tomography Treatment Outcome Ultrasonic Therapy / instrumentation, methods* |
| Chemical | |
Reg. No./Substance:
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0/Photosensitizing Agents; 1406-65-1/Chlorophyll |
| Comments/Corrections | |
Comment In:
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Integr Cancer Ther. 2010 Dec;9(4):317-9; discussion 320-1
[PMID:
21106611
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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