| Some stereological correction formulae with particular applications in quantitative neurohistology. | |
| | |
MedLine Citation:
|
PMID: 1206428 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The present report furnishes explicit formulations for correcting the observed nucleolar and nuclear volume fractions of neurons sampled on the basis of the presence of nucleolar profiles when sectioned. Such samples, frequently chosen for quantitative studies in neurohistology, can result in the overestimation ov component volume fractions. The correction formulae are derived by considering theoretical spherical models exhibiting "nucleus-nucleolus" concentricity and eccentricity, and are tested by applying them to analogous neuron populations in rat spinal cord. It is concluded that, with certain reservations, the formulae can be usefully applied to data obtained from nucleolar-biased samples, thereby increasing the reliability of quantitative information gleaned from such samples. |
| | |
Authors:
|
T M Mayhew; L M orive |
Related Documents
:
|
16271288 - Elemental analysis of soil samples for forensic purposes by inductively coupled plasma ... 22962038 - How can we improve accuracy of macroevolutionary rate estimates? 1775668 - Reaction time analysis with outlier exclusion: bias varies with sample size. 18416448 - Consultants' forum: should post hoc sample size calculations be done? 18851188 - Divide and concur: a general approach to constraint satisfaction. 22081258 - A comprehensive, computer-model-based approach for diagnosis and treatment of complex a... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of the neurological sciences Volume: 26 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 1975 Dec |
Date Detail:
|
Created Date: 1976-03-24 Completed Date: 1976-03-24 Revised Date: 2005-02-14 |
Medline Journal Info:
|
Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 503-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cell Nucleolus* Cell Nucleus Karyometry / methods* Models, Biological Nervous System / anatomy & histology*, ultrastructure |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nerve regeneration and thyroid hormone treatment.
Next Document: Oligodendroglial cell development in jimpy mice and controls. An electron-microscopic study in the o...