Document Detail

Some possible applications of computerized tomography in pathology.
MedLine Citation:
PMID:  7365009     Owner:  NLM     Status:  MEDLINE    
Computerized tomography may be adaptable to microscopic and gross pathology. Low voltage (3 to 8 keV) X-ray histologic tomography of frozen 1 to 3 mm cylinders of tissue should provide atomic-number-dependent absorption coefficients because of photoelectric capture by the common light elements in such tissue. Fixation, sectioning, and staining artifacts would be obviated. Elements of a design for a rotate-only microgantry are described. For gross pathology, existing whole body scanners could be modified by finer collimation, longer exposure times, and higher X-ray fluxes to produce tomograms of much higher resolution than is possible during life, since movement and administered radiation dose would not be problematical. Suspected pathology could be needle aspirated, thus avoiding gross dissection where it is forbidden for religious or other reasons.
W H Oldendorf
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  4     ISSN:  0363-8715     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:  1980 Apr 
Date Detail:
Created Date:  1980-06-16     Completed Date:  1980-06-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  141-4     Citation Subset:  IM    
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MeSH Terms
Radiation Dosage
Radiographic Image Enhancement / methods
Specimen Handling
Tomography, X-Ray Computed / instrumentation,  methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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