| Some neuropharmacological effects of an ethanolic extract of Maprounea africana in rodents. | |
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MedLine Citation:
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PMID: 7990488 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The ethanolic extract of the leaves of Maprounea africana (Euphorbiaceae), a medicinal plant in the Congolese traditional medicine, induced hypothermia and reduced the latency to the loss of the righting reflex and prolonged the sleeping time induced by pentobarbital in mice. It also significantly delayed the onset of clonic convulsions induced by pentylenetetrazole in mice. However, the extract did not affect either generalized convulsions induced by maximal electroshock and picrotoxin or limbic status epilepticus produced by pilocarpine and kainic acid. |
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Authors:
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P N'gouemo; C Nguemby-Bina; M Baldy-Moulinier |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of ethnopharmacology Volume: 43 ISSN: 0378-8741 ISO Abbreviation: J Ethnopharmacol Publication Date: 1994 Jul |
Date Detail:
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Created Date: 1995-01-09 Completed Date: 1995-01-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7903310 Medline TA: J Ethnopharmacol Country: IRELAND |
Other Details:
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Languages: eng Pagination: 161-6 Citation Subset: IM |
Affiliation:
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Laboratoire de Médecine Expérimentale, INSERM U249-CNRS UPR9008, Montpellier, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anticonvulsants / pharmacology* Body Temperature / drug effects Congo Hypnotics and Sedatives / pharmacology* Male Medicine, African Traditional* Mice Plant Extracts / pharmacology Plants, Medicinal* Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Hypnotics and Sedatives; 0/Plant Extracts |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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